Cassandra excels in a broad range of applications -- especially if you understand its data model and write your applications accordingly. It's an excellent choice for time-series data, and a poor choice for application queues. It performs the best if you can simply record history and compute from it, rather than going back and editing or deleting things a lot.
Titan is definitely a good choice, but it has its learning curve. The documentation may lack in places, and you might have to muster answers from different sources and technologies. But at its core, it does the job of storing and querying graph databases really well. Remember that titan itself is not the whole component, but utilizes other technologies like cassandra, gremlin, tinkerpop, etc to do many other things, and each of them has a learning curve. I would recommend titan for a team, but not for a single person. For single developer, go with Neo4j.
High Availability - we utilize the data replication features of Cassandra. This enables us to access our data even when several nodes have gone down
Data Locality - our architecture combines Cassandra storage nodes and computation nodes in the same machine. This enables us to utilize data locality and limit expensive network IO to read data.
Elasticity - Cassandra is a shared nothing architecture. Nodes can be added very easily and they discover the network topology. As soon as a node has joined the Cassandra ring, the data is redistributed among the existing nodes and streamed to it automatically.
No Ad-Hoc Queries: Cassandra data storage layer is basically a key-value storage system. This means that you must "model" your data around the queries you want to surface, rather than around the structure of the data itself.
There are no aggregations queries available in Cassandra.
The community is lacking deep documentation. I had to spend many nights trying to figure many things on my own. As graph databases will grow popular, I am sure this will be improved.
Not enough community support. Even in SO you might not find many questions. Though there are some users in SO who quickly answer graph database questions. Need more support.
I would recommend Cassandra DB to those who know their use case very well, as well as know how they are going to store and retrieve data. If you need a guarantee in data storage and retrieval, and a DB that can be linearly grown by adding nodes across availability zones and regions, then this is the database you should choose.
Apache Cassandra has the best of both worlds, it is a Java based NoSQL, linearly scalable, best in class tunable performance across different workloads, fault tolerant, distributed, masterless, time series database. We have used both Apache HBase and MongoDB for some use cases which were within hadoop setup and JSON (JavaScript Object Notation) document store respectively, but given the overall factors favoring Apache Cassandra, it is a technology choice for multiple platforms!
To be honest, titan is not as popular as Neo4j, though they do the same thing. In my personal opinion, titan has lot of potential, but Neo4j is easier to use. If the organization is big enough, it might choose titan because of its open source nature, and high scalability, but Neo4j comes with a lot of enterprise and community support, better query, better documentation, better instructions, and is also backed by leading tech companies. But titan is very strong when you consider standards. Titan follows gremlin and tinkerpop, both of which will be huge in future as more graph database vendors join the market. If things go really well, maybe Neo4j might have to support gremlin as well.
The open source version of Cassandra is only suggested for learning the basic concepts and play with its core features. Unless you really want to invest a lot in your developers and architects knowing every detail of Cassandra, I prefer the DataStax enterprise version. Although the license cost is relatively high, I think they it is worth it. I'm thinking about the support, the monitoring tool OpsCenter, and the integration of Solr and Spark (for data analysis).
Cassandra didn't fully replace our old and traditional relation database Oracle. In addition, it opens another door for us to deal with some special business use cases that NoSQL database can do better in a more feasible and efficient way.